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Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7

BACKGROUND: Aging is believed to have a close association with cardiovascular diseases, resulting in various pathological alterations in blood vessels, including vascular cell phenotypic shifts. In aging vessels, the microRNA(miRNA)-mediated mechanism regulating the vascular smooth muscle cell (VSMC...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Wang, Hongwei, Yang, Sijin, Qian, Dehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335/
https://www.ncbi.nlm.nih.gov/pubmed/31829291
http://dx.doi.org/10.1186/s40246-019-0245-z