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Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis

To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Compared to 25 WM controls, 6713 out of 18,609 genes were significantly differentially express...

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Detalles Bibliográficos
Autores principales: Elkjaer, Maria L., Frisch, Tobias, Reynolds, Richard, Kacprowski, Tim, Burton, Mark, Kruse, Torben A., Thomassen, Mads, Baumbach, Jan, Illes, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907342/
https://www.ncbi.nlm.nih.gov/pubmed/31829262
http://dx.doi.org/10.1186/s40478-019-0855-7