Cargando…
Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment
Multiple Sclerosis (MS) is the most common cause of acquired neurological disability in young adults, pathologically characterized by leukocyte infiltration of the central nervous system, demyelination of the white and grey matter, and subsequent axonal loss. Microglia are proposed to play a role in...
Autores principales: | van Wageningen, Thecla A., Vlaar, Eva, Kooij, Gijs, Jongenelen, Cornelis A. M., Geurts, Jeroen J. G., van Dam, Anne-Marie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907356/ https://www.ncbi.nlm.nih.gov/pubmed/31829283 http://dx.doi.org/10.1186/s40478-019-0850-z |
Ejemplares similares
-
Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis
por: van Wageningen, Thecla A., et al.
Publicado: (2022) -
Much, if not all, of the cortical damage in MS can be attributed to the microglial cell – Yes
por: van Wageningen, Thecla A, et al.
Publicado: (2018) -
Quantitative evidence of suppressed TMEM119 microglial immunohistochemistry in fatal morphine intoxications
por: Bohnert, Simone, et al.
Publicado: (2021) -
Tmem119-EGFP and Tmem119-CreERT2 Transgenic Mice for Labeling and Manipulating Microglia
por: Kaiser, Tobias, et al.
Publicado: (2019) -
Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin
por: van Wageningen, Thecla A., et al.
Publicado: (2021)