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Computationally efficient, exact, covariate-adjusted genetic principal component analysis by leveraging individual marker summary statistics from large biobanks

The popularization of biobanks provides an unprecedented amount of genetic and phenotypic information that can be used to research the relationship between genetics and human health. Despite the opportunities these datasets provide, they also pose many problems associated with computational time and...

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Detalles Bibliográficos
Autores principales: Wolf, Jack M., Barnard, Martha, Xia, Xueting, Ryder, Nathan, Westra, Jason, Tintle, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907735/
https://www.ncbi.nlm.nih.gov/pubmed/31797641