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Autophagy during viral infection — a double-edged sword

Autophagy is a powerful tool that host cells use to defend against viral infection. Double-membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome for degradation. Specifically, autophagy initiates an innate immune response by cooperating with pattern recognition recept...

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Detalles Bibliográficos
Autores principales: Choi, Younho, Bowman, James W., Jung, Jae U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907743/
https://www.ncbi.nlm.nih.gov/pubmed/29556036
http://dx.doi.org/10.1038/s41579-018-0003-6