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Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells

Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus, type I (HIV-1) pathogenesis. PDCs produce IFN-α and other proinflammatory cytokines through stimulation of Toll-like receptor 7 (TLR7) and TLR9...

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Detalles Bibliográficos
Autores principales: Patamawenu, Andy A., Wright, Nathaniel E., Shofner, Tulley, Evans, Sean, Manion, Maura M., Doria-Rose, Nicole, Migueles, Stephen A., Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A., Liang, C. Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Julian, Lifson, Jeffrey, Connors, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907767/
https://www.ncbi.nlm.nih.gov/pubmed/31830058
http://dx.doi.org/10.1371/journal.pone.0225806