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Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells
Plasmacytoid dendritic cells (PDCs) and their production of interferon-alpha (IFN-α) are believed to play an important role in human immunodeficiency virus, type I (HIV-1) pathogenesis. PDCs produce IFN-α and other proinflammatory cytokines through stimulation of Toll-like receptor 7 (TLR7) and TLR9...
Autores principales: | Patamawenu, Andy A., Wright, Nathaniel E., Shofner, Tulley, Evans, Sean, Manion, Maura M., Doria-Rose, Nicole, Migueles, Stephen A., Mendoza, Daniel, Peterson, Bennett, Wilhelm, Christopher, Rood, Julia, Berkley, Amy, Cogliano, Nancy A., Liang, C. Jason, Tesselaar, Kiki, Miedema, Frank, Bess, Julian, Lifson, Jeffrey, Connors, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907767/ https://www.ncbi.nlm.nih.gov/pubmed/31830058 http://dx.doi.org/10.1371/journal.pone.0225806 |
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