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Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several human cancers, such as Kaposi’s sarcoma (KS) and primary effusion lymphoma (PEL). Current treatment options for KSHV infection and virus associated diseases are sometimes ineffective, therefore, more effectively antiviral agents are urgen...

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Detalles Bibliográficos
Autores principales: Chen, Jungang, Dai, Lu, Goldstein, Alana, Zhang, Haiwei, Tang, Wei, Forrest, J. Craig, Post, Steven R., Chen, Xulin, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907871/
https://www.ncbi.nlm.nih.gov/pubmed/31790497
http://dx.doi.org/10.1371/journal.ppat.1008156