KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication

Herpesviruses usurp host cell protein synthesis machinery to convert viral mRNAs into proteins, and the endoplasmic reticulum (ER) to ensure proper folding, post-translational modification and trafficking of secreted and transmembrane viral proteins. Overloading ER folding capacity activates the unf...

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Detalles Bibliográficos
Autores principales: Johnston, Benjamin P., Pringle, Eric S., McCormick, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907875/
https://www.ncbi.nlm.nih.gov/pubmed/31790507
http://dx.doi.org/10.1371/journal.ppat.1008185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907875/
https://www.ncbi.nlm.nih.gov/pubmed/31790507
http://dx.doi.org/10.1371/journal.ppat.1008185

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