Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation

Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by which Tcf7l2 and Wnt/β-Catenin signalling elicit such a diversity of biological outcomes are poorly understood. Here, we study the function of zebrafish tcf7l2 alternative s...

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Detalles Bibliográficos
Autores principales: Young, Rodrigo M, Ewan, Kenneth B, Ferrer, Veronica P, Allende, Miguel L, Godovac-Zimmermann, Jasminka, Dale, Trevor C, Wilson, Stephen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908431/
https://www.ncbi.nlm.nih.gov/pubmed/31829936
http://dx.doi.org/10.7554/eLife.51447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908431/
https://www.ncbi.nlm.nih.gov/pubmed/31829936
http://dx.doi.org/10.7554/eLife.51447

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