Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape

High-content phenotypic screening has become the approach of choice for drug discovery due to its ability to extract drug-specific multi-layered data. In the field of epigenetics, such screening methods have suffered from a lack of tools sensitive to selective epigenetic perturbations. Here we descr...

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Detalles Bibliográficos
Autores principales: Farhy, Chen, Hariharan, Santosh, Ylanko, Jarkko, Orozco, Luis, Zeng, Fu-Yue, Pass, Ian, Ugarte, Fernando, Forsberg, E Camilla, Huang, Chun-Teng, Andrews, David W, Terskikh, Alexey V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908434/
https://www.ncbi.nlm.nih.gov/pubmed/31637999
http://dx.doi.org/10.7554/eLife.49683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908434/
https://www.ncbi.nlm.nih.gov/pubmed/31637999
http://dx.doi.org/10.7554/eLife.49683

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