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Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape
High-content phenotypic screening has become the approach of choice for drug discovery due to its ability to extract drug-specific multi-layered data. In the field of epigenetics, such screening methods have suffered from a lack of tools sensitive to selective epigenetic perturbations. Here we descr...
Autores principales: | Farhy, Chen, Hariharan, Santosh, Ylanko, Jarkko, Orozco, Luis, Zeng, Fu-Yue, Pass, Ian, Ugarte, Fernando, Forsberg, E Camilla, Huang, Chun-Teng, Andrews, David W, Terskikh, Alexey V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908434/ https://www.ncbi.nlm.nih.gov/pubmed/31637999 http://dx.doi.org/10.7554/eLife.49683 |
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