Caveolin-2 deficiency induces a rapid anti-tumor immune response prior to regression of implanted murine lung carcinoma tumors

Immunosuppression is critical for tumor growth and metastasis as well as obstacle to effective immunotherapy. Here, we demonstrate that host deficiency in caveolin-2, a member of caveolin protein family, increases M1-polarized tumor-associated macrophage (TAM) and CD8 T cell infiltration into subcut...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yajun, Qi, Xiaoqiang, Li, Guangfu, Sowa, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908574/
https://www.ncbi.nlm.nih.gov/pubmed/31831780
http://dx.doi.org/10.1038/s41598-019-55368-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908574/
https://www.ncbi.nlm.nih.gov/pubmed/31831780
http://dx.doi.org/10.1038/s41598-019-55368-4

Ejemplares similares