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One-step artificial antigen presenting cell-based vaccines induce potent effector CD8 T cell responses

The production and wide use of artificial antigen presenting cells (aAPCs) in the clinic as cancer immunotherapeutics are hindered by the need of identifying immunogenic cancer antigens and production of recombinant patient-specific major histocompatibility complexes (MHC) loaded with these peptides...

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Detalles Bibliográficos
Autores principales: Su, Qingtai, Igyártó, Botond Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908577/
https://www.ncbi.nlm.nih.gov/pubmed/31831802
http://dx.doi.org/10.1038/s41598-019-55286-5