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Comparative proteomics reveals unexpected quantitative phosphorylation differences linked to platelet activation state

There is a need to assess platelet activation in patients with thrombotic disorders. P-selectin and activated integrin αIIbβ3 are usually quantified by flow cytometry to measure platelet activation. Monitoring changes in vasodilator-stimulated phosphoprotein (VASP) phosphorylation is an established...

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Detalles Bibliográficos
Autores principales: Schmidt, G. J., Reumiller, C. M., Ercan, H., Resch, U., Butt, E., Heber, S., Liutkevičiūte, Z., Basílio, J., Schmid, J. A., Assinger, A., Jilma, B., Zellner, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908631/
https://www.ncbi.nlm.nih.gov/pubmed/31831789
http://dx.doi.org/10.1038/s41598-019-55391-5