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Murine infection with bioluminescent Leishmania infantum axenic amastigotes applied to drug discovery

Leishmaniasis is an important vector-borne neglected tropical disease caused by Leishmania parasites. Current anti-Leishmania chemotherapy is unsatisfactory, justifying the continued search for alternative treatment options. Herein, we demonstrate that luciferase-expressing Leishmania infantum axeni...

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Detalles Bibliográficos
Autores principales: Mendes Costa, David, Cecílio, Pedro, Santarém, Nuno, Cordeiro-da-Silva, Anabela, Tavares, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908656/
https://www.ncbi.nlm.nih.gov/pubmed/31831809
http://dx.doi.org/10.1038/s41598-019-55474-3