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Tuning the in vitro sensing and signaling properties of cyanobacterial PII protein by mutation of key residues

PII proteins comprise an ancient superfamily of signal transduction proteins, widely distributed among all domains of life. In general, PII proteins measure and integrate the current carbon/nitrogen/energy status of the cell through interdependent binding of ATP, ADP and 2-oxogluterate. In response...

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Detalles Bibliográficos
Autores principales: Selim, Khaled A., Haffner, Michael, Watzer, Björn, Forchhammer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908673/
https://www.ncbi.nlm.nih.gov/pubmed/31831819
http://dx.doi.org/10.1038/s41598-019-55495-y