Cargando…

Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization

Senescence is induced by various stimuli such as oncogene expression and telomere shortening, referred to as oncogene-induced senescence (OIS) and replicative senescence (RS), respectively, and accompanied by global transcriptional alterations and 3D genome reorganization. Here, we demonstrate that...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwasaki, Osamu, Tanizawa, Hideki, Kim, Kyoung-Dong, Kossenkov, Andrew, Nacarelli, Timothy, Tashiro, Sanki, Majumdar, Sonali, Showe, Louise C., Zhang, Rugang, Noma, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908677/
https://www.ncbi.nlm.nih.gov/pubmed/31831736
http://dx.doi.org/10.1038/s41467-019-13604-5