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The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.
BP180, also termed collagen XVII, is a hemidesmosomal transmembrane glycoprotein expressed in basal keratinocytes, and functions as a cell-matrix adhesion molecule in the dermal-epidermal junction of the skin. Its function other than cell-matrix adhesion remains unclear. We generated a mouse strain...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908749/ https://www.ncbi.nlm.nih.gov/pubmed/31435021 http://dx.doi.org/10.1038/s41388-019-0961-9 |