Engineering enzymatic assembly lines to produce new antibiotics

Numerous important therapeutic agents, including widely-used antibiotics, anti-cancer drugs, immunosuppressants, agrochemicals and other valuable compounds, are produced by microorganisms. Many of these are biosynthesised by modular enzymatic assembly line polyketide synthases, non-ribosomal peptide...

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Detalles Bibliográficos
Autores principales: Bozhüyük, Kenan AJ, Micklefield, Jason, Wilkinson, Barrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Biology 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908967/
https://www.ncbi.nlm.nih.gov/pubmed/31743841
http://dx.doi.org/10.1016/j.mib.2019.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908967/
https://www.ncbi.nlm.nih.gov/pubmed/31743841
http://dx.doi.org/10.1016/j.mib.2019.10.007

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