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Silencing of CHFR Sensitizes Gastric Carcinoma to PARP Inhibitor Treatment
CHFR is a tumor suppressor that not only recognizes poly(ADP-ribosylation) (PARylation) signals at the sites of DNA damage but also is downregulated in many types of cancer. However, the underlying mechanism linking its role in PARylation-mediated DNA damage repair and tumor suppression is unclear....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909066/ https://www.ncbi.nlm.nih.gov/pubmed/31812083 http://dx.doi.org/10.1016/j.tranon.2019.10.004 |