Systems-wide analysis unravels the new roles of CCM signal complex (CSC)

Cerebral cavernous malformations (CCMs) are characterized by abnormally dilated intracranial capillaries that result in increased susceptibility to stroke. Three genes have been identified as causes of CCMs; KRIT1 (CCM1), MGC4607 (CCM2) and PDCD10 (CCM3); one of them is disrupted in most CCM cases....

Descripción completa

Detalles Bibliográficos
Autores principales: Abou-Fadel, Johnathan, Vasquez, Mariana, Grajeda, Brian, Ellis, Cameron, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909108/
https://www.ncbi.nlm.nih.gov/pubmed/31872111
http://dx.doi.org/10.1016/j.heliyon.2019.e02899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909108/
https://www.ncbi.nlm.nih.gov/pubmed/31872111
http://dx.doi.org/10.1016/j.heliyon.2019.e02899

Ejemplares similares