Anticancer Molecule Discovery via C2-Substituent Promoted Oxidative Coupling of Indole and Enolate

C2, C3-disubstituted indole is one of the most frequently encountered motifs in bioactive alkaloids and medicinal chemistry. Thus, developing novel, concise, and efficient access to it is highly desired in drug discovery. Herein, we present such an approach to this scaffold by direct oxidative coupl...

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Detalles Bibliográficos
Autores principales: Lu, Helin, Zhu, Guirong, Tang, Tiange, Ma, Zhuang, Chen, Qin, Chen, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909134/
https://www.ncbi.nlm.nih.gov/pubmed/31786518
http://dx.doi.org/10.1016/j.isci.2019.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909134/
https://www.ncbi.nlm.nih.gov/pubmed/31786518
http://dx.doi.org/10.1016/j.isci.2019.11.021

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