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Anticancer Molecule Discovery via C2-Substituent Promoted Oxidative Coupling of Indole and Enolate
C2, C3-disubstituted indole is one of the most frequently encountered motifs in bioactive alkaloids and medicinal chemistry. Thus, developing novel, concise, and efficient access to it is highly desired in drug discovery. Herein, we present such an approach to this scaffold by direct oxidative coupl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909134/ https://www.ncbi.nlm.nih.gov/pubmed/31786518 http://dx.doi.org/10.1016/j.isci.2019.11.021 |