Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization

Age-related macular degeneration (AMD) is a progressive retinal disorder characterized by imbalanced pro- and antiangiogenic signals. The aim of this study was to evaluate the effect of ex vivo cell-based gene therapy with stable expression of human pigment epithelium-derived factor (PEDF) release u...

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Detalles Bibliográficos
Autores principales: Hernandez, Maria, Recalde, Sergio, Garcia-Garcia, Laura, Bezunartea, Jaione, Miskey, Csaba, Johnen, Sandra, Diarra, Sabine, Sebe, Attila, Rodriguez-Madoz, Juan Roberto, Pouillot, Severine, Marie, Corinne, Izsvák, Zsuzsanna, Scherman, Daniel, Kropp, Martina, Prosper, Felipe, Thumann, Gabriele, Ivics, Zoltán, Garcia-Layana, Alfredo, Fernandez-Robredo, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909167/
https://www.ncbi.nlm.nih.gov/pubmed/31890733
http://dx.doi.org/10.1016/j.omtm.2019.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909167/
https://www.ncbi.nlm.nih.gov/pubmed/31890733
http://dx.doi.org/10.1016/j.omtm.2019.10.013

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