Triggering apoptosis by oroxylin A through caspase-8 activation and p62/SQSTM1 proteolysis

Emerging evidence suggests that oroxylin A exhibits antitumor effects by inducing cell apoptosis. However, the involved molecular mechanisms have not been elucidated. Here we report that the apoptosis induced by oroxylin A was dependent on p62-mediated activation of caspase-8 in hepatocellular carci...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Zhu, Qin, Bu, Xiumin, Zhou, Yihui, Bai, Dongsheng, Guo, Qinglong, Gao, Yuan, Lu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909190/
https://www.ncbi.nlm.nih.gov/pubmed/31926620
http://dx.doi.org/10.1016/j.redox.2019.101392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909190/
https://www.ncbi.nlm.nih.gov/pubmed/31926620
http://dx.doi.org/10.1016/j.redox.2019.101392

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