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Triggering apoptosis by oroxylin A through caspase-8 activation and p62/SQSTM1 proteolysis
Emerging evidence suggests that oroxylin A exhibits antitumor effects by inducing cell apoptosis. However, the involved molecular mechanisms have not been elucidated. Here we report that the apoptosis induced by oroxylin A was dependent on p62-mediated activation of caspase-8 in hepatocellular carci...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909190/ https://www.ncbi.nlm.nih.gov/pubmed/31926620 http://dx.doi.org/10.1016/j.redox.2019.101392 |