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Blocking extracellular Galectin-3 in patients with osteoarthritis

OBJECTIVE: This pilot clinical trial examined the efficacy of blocking extracellular Galectin-3 (Gal-3) with modified citrus pectin (MCP), in patients suffering from knee osteoarthritis (OA). METHODS: 50 patients were randomized in a 1:1 ratio to receive MCP or placebo at a dose of 4 g (5 capsules)...

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Detalles Bibliográficos
Autores principales: Andrews, Alec R., Fernandes, Ana D., Brownmiller, Seth E., Hanna, Yousif, Fisher, Mark C., Huang, Christene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909224/
https://www.ncbi.nlm.nih.gov/pubmed/31872160
http://dx.doi.org/10.1016/j.conctc.2019.100500