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Endosomal TLR-8 Senses microRNA-1294 Resulting in the Production of NFḱB Dependent Cytokines

The primary function of toll-like receptor 8 (TLR-8) is the detection of viruses and other microbial pathogens. Recent evidence suggests that TLR-8 also senses host microRNAs (miRNAs) and implicate TLR-8 in autoimmune disorders. This study examined the interaction between miR-1294 and TLR-8. We firs...

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Detalles Bibliográficos
Autores principales: Pluta, Linda, Yousefi, Babak, Damania, Blossom, Khan, Asma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909240/
https://www.ncbi.nlm.nih.gov/pubmed/31867014
http://dx.doi.org/10.3389/fimmu.2019.02860