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ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease

BACKGROUND: Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we aimed to investigate the effect of the APOE-ABCA7 interaction on default mod...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Ting, Hsu, Shih-Wei, Huang, Shu-Hua, Huang, Chi-Wei, Chang, Wen-Neng, Lien, Chia-Yi, Lee, Jun-Jun, Lee, Chen-Chang, Chang, Chiung-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909474/
https://www.ncbi.nlm.nih.gov/pubmed/31831047
http://dx.doi.org/10.1186/s13195-019-0563-3