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ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease
BACKGROUND: Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we aimed to investigate the effect of the APOE-ABCA7 interaction on default mod...
Autores principales: | Chang, Ya-Ting, Hsu, Shih-Wei, Huang, Shu-Hua, Huang, Chi-Wei, Chang, Wen-Neng, Lien, Chia-Yi, Lee, Jun-Jun, Lee, Chen-Chang, Chang, Chiung-Chih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909474/ https://www.ncbi.nlm.nih.gov/pubmed/31831047 http://dx.doi.org/10.1186/s13195-019-0563-3 |
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