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Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

Multiplexed single-cell RNA-seq analysis of multiple samples using pooling is a promising experimental design, offering increased throughput while allowing to overcome batch variation. To reconstruct the sample identify of each cell, genetic variants that segregate between the samples in the pool ha...

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Detalles Bibliográficos
Autores principales: Huang, Yuanhua, McCarthy, Davis J., Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909514/
https://www.ncbi.nlm.nih.gov/pubmed/31836005
http://dx.doi.org/10.1186/s13059-019-1865-2