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Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference
Multiplexed single-cell RNA-seq analysis of multiple samples using pooling is a promising experimental design, offering increased throughput while allowing to overcome batch variation. To reconstruct the sample identify of each cell, genetic variants that segregate between the samples in the pool ha...
Autores principales: | Huang, Yuanhua, McCarthy, Davis J., Stegle, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909514/ https://www.ncbi.nlm.nih.gov/pubmed/31836005 http://dx.doi.org/10.1186/s13059-019-1865-2 |
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