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ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential

BACKGROUND: Histamine is a key mediator of the anti-inflammatory activity conferred by the probiotic organism Lactobacillus reuteri ATCC PTA 6475 in animal models of colitis and colorectal cancer. In L. reuteri, histamine synthesis and secretion requires l-histidine decarboxylase and a l-histidine/h...

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Detalles Bibliográficos
Autores principales: Hall, Anne E., Engevik, Melinda A., Oezguen, Numan, Haag, Anthony, Versalovic, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909576/
https://www.ncbi.nlm.nih.gov/pubmed/31830990
http://dx.doi.org/10.1186/s12934-019-1264-0