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ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential
BACKGROUND: Histamine is a key mediator of the anti-inflammatory activity conferred by the probiotic organism Lactobacillus reuteri ATCC PTA 6475 in animal models of colitis and colorectal cancer. In L. reuteri, histamine synthesis and secretion requires l-histidine decarboxylase and a l-histidine/h...
Autores principales: | Hall, Anne E., Engevik, Melinda A., Oezguen, Numan, Haag, Anthony, Versalovic, James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909576/ https://www.ncbi.nlm.nih.gov/pubmed/31830990 http://dx.doi.org/10.1186/s12934-019-1264-0 |
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