Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads

BACKGROUND: Circular DNA has recently been identified across different species including human normal and cancerous tissue, but short-read mappers are unable to align many of the reads crossing circle junctions hence limiting their detection from short-read sequencing data. RESULTS: Here, we propose...

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Detalles Bibliográficos
Autores principales: Prada-Luengo, Iñigo, Krogh, Anders, Maretty, Lasse, Regenberg, Birgitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909605/
https://www.ncbi.nlm.nih.gov/pubmed/31830908
http://dx.doi.org/10.1186/s12859-019-3160-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909605/
https://www.ncbi.nlm.nih.gov/pubmed/31830908
http://dx.doi.org/10.1186/s12859-019-3160-3

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