Cargando…
Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads
BACKGROUND: Circular DNA has recently been identified across different species including human normal and cancerous tissue, but short-read mappers are unable to align many of the reads crossing circle junctions hence limiting their detection from short-read sequencing data. RESULTS: Here, we propose...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909605/ https://www.ncbi.nlm.nih.gov/pubmed/31830908 http://dx.doi.org/10.1186/s12859-019-3160-3 |