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N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21

BACKGROUND: N-myc downstream-regulated gene 1 (NDRG1) has been shown to play a key role in tumor metastasis. Recent studies demonstrate that NDRG1 can suppress tumor growth and is related to tumor proliferation; however, the mechanisms underlying these effects remain obscure. METHODS: Immunohistoche...

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Detalles Bibliográficos
Autores principales: Zhang, Sen, Yu, Chaoran, Yang, Xiao, Hong, Hiju, Lu, Jiaoyang, Hu, Wenjun, Hao, Xiaohui, Li, Shuchun, Aikemu, Batuer, Yang, Guang, He, Zirui, Zhang, Luyang, Xue, Pei, Cai, Zhenghao, Ma, Junjun, Zang, Lu, Feng, Bo, Yuan, Fei, Sun, Jing, Zheng, Minhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909641/
https://www.ncbi.nlm.nih.gov/pubmed/31831018
http://dx.doi.org/10.1186/s13046-019-1476-5