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SMAD4 Somatic Mutations in Head and Neck Carcinoma Are Associated With Tumor Progression

As the incidence and the mortality rate of head and neck squamous cell carcinoma (HNSCC) is increasing worldwide, gaining knowledge about the genomic changes which happen in the carcinogenesis of HNSCC is essential for the diagnosis and therapy of the disease. SMAD4 (DPC4) is a tumor suppressor gene...

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Detalles Bibliográficos
Autores principales: Lin, Li-Han, Chang, Kuo-Wei, Cheng, Hui-Wen, Liu, Chung-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909744/
https://www.ncbi.nlm.nih.gov/pubmed/31867281
http://dx.doi.org/10.3389/fonc.2019.01379