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Is Rapamycin a Dietary Restriction Mimetic?

Since the initial suggestion that rapamycin, an inhibitor of target of rapamycin (TOR) nutrient signaling, increased lifespan comparable to dietary restriction, investigators have viewed rapamycin as a potential dietary restriction mimetic. Both dietary restriction and rapamycin increase lifespan ac...

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Detalles Bibliográficos
Autores principales: Unnikrishnan, Archana, Kurup, Kavitha, Salmon, Adam B, Richardson, Arlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909904/
https://www.ncbi.nlm.nih.gov/pubmed/30854544
http://dx.doi.org/10.1093/gerona/glz060