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Orai1 Promotes Osteosarcoma Metastasis by Activating the Ras-Rac1-WAVE2 Signaling Pathway

BACKGROUND: The purpose of this study was to investigate whether Orai1 plays a role in the metastasis of osteosarcoma. MATERIAL/METHODS: The expression of Orai1 was silenced by small interfering RNAs against Orai1 (Orai1 siRNA) in osteosarcoma MG-63 cells. Various experiments were carried out to det...

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Detalles Bibliográficos
Autores principales: Guo, Yunshan, Zhu, Jinwen, Wang, Xiaodong, Li, Ruoyu, Jiang, Kuo, Chen, Shi, Fan, Jinzhu, Xue, Liujie, Hao, Dingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909920/
https://www.ncbi.nlm.nih.gov/pubmed/31796725
http://dx.doi.org/10.12659/MSM.919594