Fenretinide-induced Apoptosis of Acute Myeloid Leukemia Cells via NR4A1 Translocation into Mitochondria and Bcl-2 Transformation

OBJECTIVE: Fenretinide is reported to induce NR4A1-associated apoptosis in several types of cancer cells. However, it remains unclear about its specific role and the underlying mechanism in acute myeloid leukemia (AML). Therefore, this study aimed to explore the role and mechanism of fenretinide-ind...

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Detalles Bibliográficos
Autores principales: Xiong, Jie, Kuang, Xingyi, Lu, Tingting, Liu, Xu, Cheng, Bingqing, Wang, Weili, Wei, Danna, Li, Xinyao, Zhang, Zhaoyuan, Fang, Qin, Wu, Depei, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909957/
https://www.ncbi.nlm.nih.gov/pubmed/31839811
http://dx.doi.org/10.7150/jca.32167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909957/
https://www.ncbi.nlm.nih.gov/pubmed/31839811
http://dx.doi.org/10.7150/jca.32167

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