Spexin alleviates insulin resistance and inhibits hepatic gluconeogenesis via the FoxO1/PGC-1α pathway in high-fat-diet-induced rats and insulin resistant cells

Objective: Recent studies demonstrate circulating serum spexin levels are reduced in obesity or type 2 diabetes mellitus (T2DM) patients and may play a role in glucose metabolism. The mechanism underlying is not known. In this study, we explore whether spexin has a role in insulin resistance and hep...

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Detalles Bibliográficos
Autores principales: Gu, Liping, Ding, Xiaoying, Wang, Yufan, Gu, Mingyu, Zhang, Jielei, Yan, Shuai, Li, Na, Song, Zhiyi, Yin, Jiajing, Lu, Leilei, Peng, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909969/
https://www.ncbi.nlm.nih.gov/pubmed/31853220
http://dx.doi.org/10.7150/ijbs.31781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909969/
https://www.ncbi.nlm.nih.gov/pubmed/31853220
http://dx.doi.org/10.7150/ijbs.31781

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