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Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation

BACKGROUND: Baicalein, a natural flavonoid derived from traditional Chinese herb Scutellaria baicalensis Georg (known as Huang Qin in Chinese), has been reported to exhibit notable antitumor activity in various cancer cells, including breast cancer. However, the detailed mechanisms underlying its in...

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Detalles Bibliográficos
Autores principales: Liu, Zheng-Hong, Yang, Cheng-Xi, Zhang, Lei, Yang, Cong-Ying, Xu, Xiu-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910096/
https://www.ncbi.nlm.nih.gov/pubmed/31849483
http://dx.doi.org/10.2147/OTT.S222819