Parallel Accelerated Evolution in Distant Hibernators Reveals Candidate Cis Elements and Genetic Circuits Regulating Mammalian Obesity

Obesity is a clinical problem and an important adaptation in many species. Hibernating mammals, for example, become obese, insulin resistant, and hyperinsulinemic to store fat. Here, we combine comparative phylogenomics with large-scale human genome data to uncover candidate cis elements and genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferris, Elliott, Gregg, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910134/
https://www.ncbi.nlm.nih.gov/pubmed/31775032
http://dx.doi.org/10.1016/j.celrep.2019.10.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910134/
https://www.ncbi.nlm.nih.gov/pubmed/31775032
http://dx.doi.org/10.1016/j.celrep.2019.10.102

Ejemplares similares