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Parallel Accelerated Evolution in Distant Hibernators Reveals Candidate Cis Elements and Genetic Circuits Regulating Mammalian Obesity
Obesity is a clinical problem and an important adaptation in many species. Hibernating mammals, for example, become obese, insulin resistant, and hyperinsulinemic to store fat. Here, we combine comparative phylogenomics with large-scale human genome data to uncover candidate cis elements and genetic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910134/ https://www.ncbi.nlm.nih.gov/pubmed/31775032 http://dx.doi.org/10.1016/j.celrep.2019.10.102 |