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Isomeric triazines exhibit unique profiles of bioorthogonal reactivity
Expanding the scope of bioorthogonal reactivity requires access to new and mutually compatible reagents. We report here that 1,2,4-triazines can be tuned to exhibit unique reaction profiles with biocompatible strained alkenes and alkynes. Computational analyses were used to identify candidate orthog...
Autores principales: | Kamber, David N., Nguyen, Sean S., Liu, Fang, Briggs, Jeffrey S., Shih, Hui-Wen, Row, R. David, Long, Zane G., Houk, K. N., Liang, Yong, Prescher, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910137/ https://www.ncbi.nlm.nih.gov/pubmed/31908754 http://dx.doi.org/10.1039/c9sc01427f |
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