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Drug resistance-related sunitinib sequestration in autophagolysosomes of endothelial cells

Our previous study demonstrated that the tyrosine kinase receptor inhibitor sunitinib induces acquired drug resistance in endothelial cells. The present study explored the role of lysosomal sequestration of sunitinib in the acquisition of drug resistance in human microcapillary endothelial HMEC-1 ce...

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Detalles Bibliográficos
Autores principales: Wu, Shuang, Huang, Limin, Shen, Rong, Bernard-Cacciarella, Melanie, Zhou, Pei, Hu, Chaoquan, Di Benedetto, Melanie, Janin, Anne, Bousquet, Guilhem, Li, Hong, He, Zhixu, Lu, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910192/
https://www.ncbi.nlm.nih.gov/pubmed/31789391
http://dx.doi.org/10.3892/ijo.2019.4924