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UNC5C-knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin α6/β4 signaling pathway

Unc-5 Netrin Receptor C (UNC5C) is a netrin-1 dependence receptor that mediates the induction of apoptosis in the absence of netrin-1. The present study found that UNC5C is heterogeneously expressed in breast cancer cell lines. By knocking down UNC5C in SK-BR-3 and ZR-75-30 cells and overexpressing...

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Detalles Bibliográficos
Autores principales: Yuan, Mingjing, Xie, Fuan, Xia, Xianyuan, Zhong, Kai, Lian, Lanlan, Zhang, Shihui, Yuan, Li, Ye, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910211/
https://www.ncbi.nlm.nih.gov/pubmed/31789389
http://dx.doi.org/10.3892/ijo.2019.4931