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Misregulation of Drosophila Myc Disrupts Circadian Behavior and Metabolism

Drosophila Myc (dMyc) is highly conserved and functions as a transcription factor similar to mammalian Myc. We previously found that oncogenic Myc disrupts the molecular clock in cancer cells. Here, we demonstrate that misregulation of dMyc expression affects Drosophila circadian behavior. dMyc over...

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Detalles Bibliográficos
Autores principales: Hsieh, Annie L., Zheng, Xiangzhong, Yue, Zhifeng, Stine, Zachary E., Mancuso, Anthony, Rhoades, Seth D., Brooks, Rebekah, Weljie, Aalim M., Eisenman, Robert N., Sehgal, Amita, Dang, Chi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910219/
https://www.ncbi.nlm.nih.gov/pubmed/31722196
http://dx.doi.org/10.1016/j.celrep.2019.10.022